Lions Mane: Backed by Science

Several studies have investigated the effects of lion's mane. We have compiled the most interesting results related to cognitive health, mood, anxiety, and sleep.

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  • Study 1

    Study type:
    Randomised, double-blind, placebo-controlled trial

    To examine the effect of yamabushitake (Lion’s Mane) on patients with mild-cognitive impairments.

    Method of evaluation:
    Cognitive impairment was evaluated using the researchers’ self-developed cognitive assessment tool. It consisted of verbal questions and tasks that assess memory, attention, language, and visual-motor skills, providing a score that helps identify potential cognitive impairments.

    1000 mg/day (4 x 250 mg containing 96% lion’s mane) or placebo

    29 men and women aged 50 to 80 years old
    16 weeks

  • Results

    The study found an association between 1000mg of lion’s mane intake and a significant increase in cognitive function at weeks 8, 12, and 16 of the trial. The researchers also observed that the cognitive function of 71.4% of participants in the lion's mane group improved significantly, compared to only 6.6% in the placebo group. The cognitive function remained unchanged in the majority of the placebo group (86.7%) after 6 weeks, compared to only 1 participant (6.7%) in the Lion's mane group. No adverse effects of lion's mane were reported