Scientific Studies
Magnesium
Scientific Study
Insomnia
Study type:
Randomised, double-blind, placebo-controlled trial
Purpose:
To investigate the effect of magnesium supplementation on insomnia in elderly.
Method of evaluation:
Insomnia was assessed using the Insomnia Severity Index (ISI), a seven-item questionnaire measuring sleep difficulties and satisfaction. Participants also kept daily sleep logs to track their sleep time.
Dose:
500 mg/d elemental magnesium (2 x 250 mg tablets) or placebo
Participants:
43 men and women with an average age of 65 years
Duration:
8 weeks
Results:
The researchers observed that participants who took magnesium supplements had significant improvements compared to the placebo group. These included significantly longer sleep time, better sleep efficiency, higher levels of serum renin and melatonin, and a significant decrease in insomnia severity, time to fall asleep, and stress levels. They also observed trends in reduced early morning awakenings and increased magnesium levels.
Year:
2012
Link:
Scientific Study
Stress
Study type:
Randomised, single-blind, placebo-controlled trial
Purpose:
To evaluate the effects of a combination of magnesium, vitamins B6, B9, B12, rhodiola, and L-theanine (Mg-Teadiola) on stress and stress-related quality of life parameters, including sleep and pain perception, in chronically stressed individuals.
Method of evaluation:
Sleep quality was assessed before and after the intervention using the Pittsburgh Sleep Quality Index, a self-reported questionnaire which measures seven areas: subjective sleep quality, sleep latency, sleep duration, sleep efficiency, sleep disturbances, use of sleep medication, and daytime dysfunction.
Dose:
150 mg/day of magnesium with 125 mg/d L-theanine, 222 mg/d rhodiola, 0.7 mg vit B6, 0.1 mg of vit B9, and 1.25 mcg vit B12, or placebo
Participants:
100 chronically stressed, bu otherwise healthy men and women aged 18-65 years
Duration:
28 days
Results:
Mg-Teadiola showed potential for improving sleep-related quality of life, particularly in significantly reducing daytime dysfunction due to sleepiness with longer use. The study also found an association between Mg-Teadiola supplementation and significant decreases in stress scores.
Year:
2022
Link:
Scientific Study
Depression
Study type:
Case histories (Case #1)
Purpose:
To determine the effects of magnesium supplementation in individuals with major depressive disorder
Dose:
300 mg/d of magnesium as glycinate and later as taurinate
Participant:
A 59-year-old male with a history of mild depression, previously managed with antidepressants, suddenly developed severe anxiety, insomnia, muscle spasms, and suicidal depression after a year of intense stress and poor dietary habits.
Results:
The subject reported that after the first night of starting magnesium, his sleep returned to near normal. Over the next four days, depression was significantly reduced for 4-6 hours after each dose, anxiety gradually faded, and headaches quickly disappeared. In the months that followed, normalcy was maintained only by frequent magnesium ingestion.
Year:
2006
Link: